Grey's Anatomy > CastsEllen Pompeo as Dr. Meredith Grey
Meredith is the eponymous character of the series and her voice-over is usually the narration at the beginning and end of the show. Many people call in the 3rd season have called her "Dark and Twisty" and "Scary and Damaged". A graduate of Dartmouth Colle... Sandra Oh as Dr. Cristina Yang
A doctor of Korean descent raised in Judaism (her mother converted on re-marriage) and a native of Beverly Hills, Los Angeles, Yang is not religious, but has mentioned Jewish customs from her upbringing like Shiv'ah and at times has referred to herself as... Katherine Heigl as Dr. Isobel "Izzie" Stevens
Izzie is the blonde roommate of Meredith and George. She grew up in nearby Chehalis, Washington living in a trailer park, paying her way through medical school as an underwear model. When meeting a pregnant teenage girl from her hometown, she revealed tha... Justin Chambers as Dr. Alex Karev
A former wrestler at the University of Iowa. Alex became a wrestler because his father used to beat his mother, Alex beat up his father after his father hit his mother. Alex's father ended up in the hospital and he left Alex and his mother after the incid... T.R. Knight as Dr. George O'Malley
One of Meredith's roommates, he formerly had an infatuation with Meredith which he only recently admitted, and ended up having a one-night stand with her. She cried during their encounter. Often the most emotional of the male doctors, he sometimes gets in... Chandra Wilson as Dr. Miranda Bailey
A graduate of Wellesley College, Miranda Bailey is a resident surgeon who is also in charge of the five interns, Bailey earned the nickname "The Nazi" for her tough personality. She gave birth to son, William George Bailey Jones, during a bomb scare, whil... James Pickens Jr. as Dr. Richard Webber
The current Chief of Surgery at Seattle Grace. He had an affair with intern Meredith's mother, Ellis Grey (which he did not know his wife knew about). He is a recovered alcoholic ("Superstition"). His niece is dying of ovarian cancer. His wife, Adelle, as... Isaiah Washington as Dr. Preston Burke
The chief cardiothoracic surgeon at Seattle Grace. After completing pre-medical studies at Tulane University, Burke graduated first in his class from Johns Hopkins Medical School, not because he was necessarily the most talented nor the smartest, but beca... Patrick Dempsey as Dr. Derek Shepherd
Head of neurosurgery at SGH, the interns have nicknamed him "McDreamy" for his good looks. He was in a relationship with Meredith beginning in the first episode, but abruptly ended it when his estranged wife, Dr. Addison Forbes Montgomery Shepherd, arrive... Kate Walsh as Dr. Addison Montgomery-Shepherd
A highly regarded neo-natal surgeon; while married to Derek, she had an affair with his best friend, plastic surgeon Dr. Mark Sloan, prompting Derek to leave New York for Seattle. Dr. Webber brings her to Seattle Grace for a consult on a difficult case an... Steven W. Bailey as Joe
The owner of the Emerald City Bar-across the hospital- where the doctors often go for a drink. Also where Derek and Meredith met. | 
