 | Late Night with Conan O'Brien 10th Anniversary Special | 000 | 09/14/03 |
| Jon Lovitz, Wilmer Valderrama, Jet | 001 | 09/03/03 |
| Gary Sinise, Seth Green, Tanya Streeter | 002 | 09/04/03 |
| David Spade, Sara Rue, Jim Gaffigan | 003 | 09/05/03 |
| Michael Caine, Jason Biggs, Joss Stone | 004 | 09/16/03 |
| Christina Ricci, Michael Rapaport, The Folksmen | 005 | 09/17/03 |
| Charlie Sheen, Scarlett Johansson, My Morning Jacket | 006 | 09/18/03 |
| Kelsey Grammer, Craig Bierko, Greg Giraldo | 007 | 09/19/03 |
| Kevin James, Ken Burns, Teri Polo | 008 | 09/23/03 |
| Whoopi Goldberg, Rosario Dawson, Eastmountainsouth | 009 | 09/24/03 |
| Diane Lane, Wanda Sykes, Jonny Lang | 010 | 09/25/03 |
| The Rock, Isaac Mizrahi, Robert Randolph & the Family Band | 011 | 09/26/03 |
| Alec Baldwin, Vanessa Marcil, Rancid | 012 | 09/30/03 |
| Val Kilmer, Carmen Electra, Todd Barry | 013 | 10/01/03 |
| Jack Black, Christopher Walken, Staind | 014 | 10/02/03 |
| Lisa Kudrow, Jeremy Piven, Granddaddy | 015 | 10/03/03 |
| Kevin Bacon, Vivica A. Fox, The Del McCoury Band | 016 | 10/07/03 |
| Lucy Lui, Michael Moore, Gov't Mule | 017 | 10/08/03 |
| Uma Thurman, Josh Lucas, North Mississippi All-Stars | 018 | 10/09/03 |
| Gwyneth Paltrow, Philip Seymour Hoffman, Howie Day | 019 | 10/10/03 |
| Tim Robbins, Natasha Henstridge, Kaki King | 020 | 10/16/03 |
| David Arquette, Gina Gershon, Bela Fleck & the Flecktones | 021 | 10/17/03 |
| Norm MacDonald, Laura Prepton, Triumph the Insult Comic Dog | 022 | 10/28/03 |
| Al Franken, Courtney Thorne-Smith, The Thrills | 023 | 10/29/03 |
| Quentin Tarantino, Molly Sims, Chuck Palahniuk | 024 | 10/30/03 |
| James Caan, David Cross, Greg Behrendt | 025 | 10/31/03 |
| Patrick Stewart, Regina Hall, The Strokes | 026 | 11/04/03 |
| Lawrence Fishburne, Polyphonic Spree | 027 | 11/05/03 |
| Will Ferrell, Chloe Sevigny, Sarah Vowell | 028 | 11/06/03 |
| Darrell Hammond, Shannen Doherty, Joshua Bell | 029 | 11/07/03 |
| Ice-T, Jenna Elfman, The Strokes | 030 | 11/11/03 |
| Brendan Fraser, Marg Helgenberger, Ron Isley & Burt Bacharach | 031 | 11/12/03 |
| Dolly Parton, Steve Irwin | 032 | 11/13/03 |
| Russell Crowe, Alicia Silverstone, Andrew W.K. | 033 | 11/14/03 |
| William H. Macy, Heidi Klum, The Strokes | 034 | 11/18/03 |
| Elvis Costello, Eliza Dushku | 035 | 11/19/03 |
| Billy Bob Thorton, Nick Lachey, Rob Krueger | 036 | 11/20/03 |
| Lauren Graham, Steve Harvey, Dashboard Confessional | 037 | 11/21/03 |
| Ron Howard, John Tesh, The Strokes | 038 | 11/26/03 |
| Zach Braff, Billy Connelly, Brian Setzer Orchestra | 039 | 11/26/03 |
| Bernie Mac, Ben Chaplin, Thursday | 040 | 11/27/03 |
| Brian Williams, Maggie Gyllenhaal, Jim Gaffigan | 041 | 12/09/03 |
| Jude Law, Maggie Gyllenhaal, Michelle Branch | 042 | 12/12/03 |
| Greg Kinnear, Bob Odenkirk, Tom Shales | 043 | 12/11/02 |
| Matt Damon, Kevin Pollack, Randy Newman | 044 | 12/12/03 |
| Kelly Ripa, Tony Bennett | 045 | 12/16/03 |
| Elijah Wood, Estella Warren, Liz Phair | 046 | 12/17/03 |
| Jennifer Connelly, Lewis Black, Sam Goldstein | 047 | 12/18/03 |
| Natalie Portman, Bill O'Reilly, Patty Loveless | 048 | 12/19/03 |
| Julia Stiles, Marc Maron, Mitch Hedberg | 049 | 12/23/03 |
| Ian McKellen, Petra Nemcova, The Stills | 050 | 12/26/03 |
| Tom Brokaw, Gary Sheffield, John Mayer with Buddy Guy and Double Trouble | 051 | 12/30/03 |
| Jarod Miller, Amy Sedaris, Moby | 052 | 12/31/03 |
| Ethan Hawke, George Wendt, Natalie MacMaster | 053 | 01/02/04 |
| Tyra Banks, Andy Serkis, Los Lonely Boys | 054 | 01/13/04 |
| Benico Del Toro, Richard Lewis, Maroon 5 | 055 | 01/14/04 |
| Ben Stiller, Sarah Ferguson, Rich Hall | 056 | 01/15/04 |
| Nathan Lane, Susie Essman, The Bouncing Souls | 057 | 01/16/04 |
| Dave Chappelle, Jerry Orbach, The Candy Butchers | 058 | 01/20/04 |
| Donald Trump, Jeff Garlin, Brian Kiley | 059 | 01/21/04 |
| Ashton Kutcher, Kirstin Kreuk, Rickie Lee Jones | 060 | 01/22/04 |
| Topher Grace, Jack Osbourne, Jim McMullen | 061 | 01/23/04 |
| Al Roker, Mischa Barton, Mindy Smith. | 062 | 02/02/04 |
| Matt Lauer, Tom Cavanagh, Paul Teutul, Paul Teutul Jr., & Mikey Teutul | 063 | 02/04/04 |
| Megan Mullally, Harry Connick Jr. | 064 | 02/05/04 |
| Drew Barrymore, Paul Rudd, The Walkman | 065 | 02/06/04 |
| Mike Myers, Ron James | 066 | 02/10/04 |
| Michael J. Fox, Ken Capling, Nickelback | 067 | 02/11/04 |
| Adam Sandler, Stompin' Tom Connors | 068 | 02/12/04 |
| Jim Carrey, Eric McCormack, Barenaked Ladies | 069 | 02/13/04 |
| Meg Ryan, "Queer Eye" Guys, The Shins | 070 | 02/17/04 |
| Kirsten Davis, Omar Epps, The Holmes Brothers | 071 | 02/18/04 |
| James Spader, Ruben Studdard, Kenny Chesney | 072 | 02/19/04 |
| Walter Cronkite, Fred Armisen, Ben Harper | 073 | 02/20/04 |
| Damon Wayans, Paulie Litt, Al Green | 074 | 02/24/04 |
| Andy Garcia, Brittany Daniel, Brini Maxwell | 075 | 02/25/04 |
| Samuel L. Jackson, James Carville, Van Hunt | 076 | 02/26/04 |
| Barbara Walters, Grant Rosenmeyer, Grant Lee Philips | 077 | 02/27/04 |
| Andy Dick, Clyde Peeling, Wheat | 078 | 03/02/04 |
| Snoop Dogg, Paul Bettany, Mr. Geography | 079 | 03/03/04 |
| Michael Imperioli, Kenan Thompson, Tom Jones | 080 | 03/04/04 |
| Ben Stiller, Owen Wilson, Meredith Vieira, Cee-Lo | 081 | 03/05/04 |
| Liv Tyler, Juliette Lewis, Norah Jones | 082 | 03/09/04 |
| Jeff Goldblum, Omarosa Stallworth, Sarah McLachlan | 083 | 03/10/04 |
| Elijah Wook, Rachel Dratch, BJ Novak | 084 | 03/11/04 |
| Frankie Muniz, Big Show, Ollabelle | 085 | 03/12/04 |
| Edie Falco, Mayor Jason West, The Allman Brothers Band | 086 | 03/16/04 |
| Carson Daly, Portia de Rossi, James Lipton | 087 | 03/17/04 |
| Kate Winslet, Jamie-Lynn DiScalla, The Living End | 088 | 03/18/04 |
| Ethan Hawke, Neil Young, Omid Djalili | 089 | 03/19/04 |
| Bob Costas, Brian Posehn, Toby Lightman | 090 | 03/30/04 |
| Minnie Driver, Chris Klein, Usher | 091 | 03/31/04 |
| Al Franken, Vivica A. Fox, Scotty Nguyen | 092 | 04/01/04 |
| The Rock, Colin Quinn, The Sleep Jackson | 093 | 04/02/04 |
| Johnny Knoxville, Elisha Cuthbert, The Distillers | 094 | 04/06/04 |
| Lorraine Bracco, Bill Bellamy, Eagles of Death Metal | 095 | 04/07/04 |
| Cedric the Entertainer, Jason Bateman, Yoshi Amao | 096 | 04/08/04 |
| Tim Robbins, Larry King, Lambchop | 097 | 04/09/04 |
| Uma Thurman, Jon Favreau, Sugarcult | 098 | 04/13/04 |
| Quentin Tarantino, Rhona Mitra, Ben Kweller | 099 | 04/14/04 |
| Chris Rock, Shannon Elizabeth, Joe Buck | 100 | 04/15/04 |
| David Duchovny, Kwame Jackson, Jim Gaffigan | 101 | 04/16/04 |
| Rebecca Romijn-Stamos, Patton Oswalt, Shinedown | 102 | 04/27/04 |
| Jamie Foxx, Mark McKinney, David Feldman | 103 | 04/28/04 |
| Tina Fey, Jamie Foxx, John Mayer | 104 | 04/29/04 |
| Lindsay Lohan, Randy Jackson, Patti Smith | 105 | 04/30/04 |
| Ray Liotta, Rachel Bilson, Carly Simon | 106 | 05/04/04 |
| Andy Richter, Mila Kunis, Georges Brossard | 107 | 05/05/04 |
| Brad Pitt, Janet Jackson | 108 | 05/06/04 |
| Lauren Graham, Paula Abdul, Old Crow Medicine Show | 109 | 05/07/04 |
| Eric Bana, Amy Poehler, Sondre Lerche | 110 | 05/11/04 |
| Kelsey Grammer, Mariska Hargitay, Lewis Black | 111 | 05/12/04 |
| Jimmy Fallon, Jamie Cullum | 112 | 05/13/04 |
| ? | 113 | 05/14/04 |
| Laura Prepon, Robert Reich, Yellowcard | 114 | 05/18/04 |
| Al Roker, Harland Williams, Manny Yarbrough | 115 | 05/19/04 |
| Tom Selleck, Macaulay Culkin, Dave Attell | 116 | 05/20/04 |
| Darrell Hammond, Ben McKenzie, Switchfoot | 117 | 05/21/04 |
| Tom Arnold, Daniel Radcliffe, John Pizzarelli | 118 | 05/25/04 |
| Brian Williams, Kevin Hart, Andrew W.K. | 119 | 05/26/04 |
| Senator John McCain, George Lopez, Tom Papa | 120 | 05/27/04 |
| Mandy Morre, Susie Essman, Ambulance LTD | 121 | 05/28/04 |
| Jay Mohr, Richard Schiff, Simple Kid | 122 | 06/08/04 |
| Tom Brokaw, Steve Coogan, Mama Gena | 123 | 06/09/04 |
| Jennifer Love Hewitt, Steve Irwin, Indigo Girls | 124 | 06/10/04 |
| Ice-T, Jermey Suarez, Demetri Martin | 125 | 06/11/04 |
| Jackie Chan, Tim Russert, Franz Ferdinand | 126 | 06/15/04 |
| Matthew Broderick, Steven Wright, Patti Scialfa | 127 | 06/16/04 |
| Tom Hanks, Sam Moore with Carla Thomas | 128 | 06/17/04 |
| Gisele Bundchen, Jesse James, Auf Der Mar | 129 | 06/18/04 |
| Ashley Judd, Jeff Goldblum, Alanis Morissette | 130 | 06/22/04 |
| James Garner, Busy Philipps, Air Guitar Champion Miri Park | 131 | 06/23/04 |
| Marlon Wayans, Nicole Richie, Heart | 132 | 06/24/04 |
| Michael Moore, Patton Oswalt, Ozomatli | 133 | 06/25/04 |
| Will Ferrell, Beth Littleford, Jesse Malin | 134 | 07/06/04 |
| Christina Applegate, Marc Maron, Sonic Youth | 135 | 07/07/04 |
| John McEnroe, Sting | 136 | 07/08/04 |
| Paul Rudd, Lars Ulrich, Jim Gaffigan | 137 | 07/09/04 |
| Caroline Rhea, Jeff Garlin, Burning Brides | 138 | 07/13/04 |
| Queen Latifah, Ali G., The Roots | 139 | 07/14/04 |
| Alan Cumming, Ricky Fante | 140 | 07/15/04 |
| Randy Constan | 141 | 07/16/04 |
| Julianna Margulies, Kevin Pollak, Greg Fizsimmons | 142 | 07/20/04 |
| Benjamin Bratt, Isaac Mizrahi, Modest Mouse | 143 | 07/21/04 |
| Halle Berry, Christopher Meloni, Erinn Smart | 144 | 07/22/04 |
| Carson Daly, Laird Hamilton, D12 | 145 | 07/23/04 |
| Natalie Portman, Mark Consuelos, Los Lobos | 146 | 08/03/04 |
| Jamie Foxx, Josie Maran, Beenie Man | 147 | 08/04/04 |
| Brittany Murphy, John Cho, Louis CK | 148 | 08/05/04 |
| Jada Pinkett-Smith, Aries Spears, Sahara Hotnights | 149 | 08/06/04 |
| Seth Green, Ann Hathaway, NOFX | 150 | 08/10/04 |
| Clyde Peeling, Dax Shepard, Mutual Admiration Society | 151 | 08/11/04 |
| Compilation Show | 152 | 08/12/04 |
| Darrell Hammond, Blanchard Ryan, They Might Be Giants | 153 | 08/13/04 |
