ScrubsZach Braff as Dr. John Michael "J.D." Dorian
A wacky, fun, nervous intern turned cocky resident now attending at Sacred Heart Hospital. He wants to have the nickname "Tiger" but is either called J.D., Bambi (by Carla) or a girl's name (by Dr. Cox). Throughout the show he narrates his inner monologue. Sarah Chalke as Dr. Elliot Reid
The neurotic attending with a mission to be noticed in the medical profession. She left Sacred Heart and managed to get a fellowship which didn't last long since the cure was found. She's now back with Sacred Heart Hospital. Eliza Coupe as Denise Mahoney Donald Faison as Dr. Christopher "Chris" Duncan Turk
A cocky surgeon with a god complex. He loves to dance and has a few nicknames such as: Chocolate Bear (by J.D.), Super Chocolate Bear (by J.D.), Turkleton (by Dr. Kelso). He is an attending at Sacred Heart Hospital. He is best friends with Dr. John 'J.D.' Dorian. Ken Jenkins as Dr. Robert "Bob" Kelso
The self-centered chief of medicine at Sacred Heart Hospital. He is hated by almost all the staff at the hospital. He is considered 'Evil', he cheats on his wife, he doesn't care about anybody else and uses other people for his own personal gain. John C. McGinley as Dr. Percival "Perry" Ulysses Cox
A self-centered doctor with a heart of gold. He has a strong, cocky personality, but likes to help people in his own way. The only feelings he really shows is "I am Dr. Cox, I am the king, I hate you all" but deep down he's a great guy; he just doesn't like to show it. Judy Reyes as Nurse Carla Espinosa
A strong personality. She doesn't back down from a personal fight. She is good friends with J.D., Elliot, Dr. Cox and Laverne. Neil Flynn as The Janitor
J.D.'s arch enemy. He is the janitor of the hospital and constantly finds new ways to annoy J.D. He is good friends with Troy, "the sloppy joe guy". Even though his personality is considered "evil", there have been some occasions where he seems more "human" than he usually is. | 
