| | Ugly Betty | America Ferrera as Beatriz "Betty" U. Suarez
Betty Suarez is a young, intelligent and hardworking woman who landed her first job as an assistant in Mode, a fashion magazine. Though she knows nothing about the fashion world and has no experience in publishing, she is highly efficient and competent which makes a good tandem for Daniel, her boss. |
 | Eric Mabius as Daniel Meade
Daniel Meade is Betty's hunky boss. He is the editor-in-chief of MODE. For Betty, he is smarter than most people give him credit for. He graduated Harvard in 5 years and spent his inheritance instantly. Women seem to adore him. |
 | Tony Plana as Ignacio Suarez
Ignacio Suarez is Betty's father. He is perceived to be patriotic and hardworking. Previously, he was an amateur boxer. He loves playing dominoes and has a flare for cooking. |
 | Ana Ortiz as Hilda Suarez
Hilda Suarez is Justin's mother and Betty's sister. This former Miss Teen Queen enjoys a good sale and going to the salon. |
 | Ashley Jensen as Christina McKinney
Christina is the best friend of Betty at Mode. She is perceived to be kind and witty. She is originally from Scotland and has a flare for designing clothes. |
 | Becki Newton as Amanda Tanen
Amanda is the receptionist at MODE. She is so involved in fashion that she reads magazines all day long. Aside from this, she is an aficionado when it comes to shoes. She constantly updates her collections and throws a pair of shoes every three days. She aspires to marry a duke someday. |
 | Mark Indelicato as Justin Suarez
Justin Suarez is Betty's nephew and Hilda's son. He is an A student at Jackson Heights Middle School. He enjoys watching Fashion TV marathons and has a unique interest in the fashion world. |
Vanessa Williams as Wilhelmina Slater
Wilhemina Slator is the woman you love to hate. The classic woman who is always up to something. In this case, she was looked over for the job of editor-in-chief of MODE magazine. Now, she's doing whatever she can in any way of form to get the job, which she believes she was born to do.  | Michael Urie as Marc St. James
Marc is the openly gay assistant of Wilhelmina. He is extremely loyal to Wilhelmina and is willing to do everything for the success of his boss. He simply adores Desperate Housewives and Project Catwalk. |
Judith Light as Claire Meade
The drunk mother of Daniel and Alex Meade. She loves her children so much as to do anything to protect them.  | Alan Dale as Bradford Meade
Bradford Meade is the founder and the president of Meade Publications. He is also the father of Daniel Meade. |
Rebecca Romijn as Alexis Meade
Alex was Daniel's brother who was reborn as Alexis Meade, a now full-fledge woman. Alex and Daniel are always in competition with each other even when they were children. Christopher Gorham as Henry Grubstick
Henry works at Meade's accounting department. Henry enters the scene and complicates Betty's love life when he got between her and Walter. Kevin Sussman as Walter
Walter is Betty's boyfriend. Thoughtful and understanding, he shares similar interests with Betty. He works at Pro-Buy, a Circuit City type electronics store and is a whiz at fixing equipment. |
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